Chrissy Metz Opens Up About Taking a GLP-1 After Years of Skepticism & the Unexpected Change She Noticed First Was Not Physical

Aug 14, 2026 by apost team

Chrissy Metz spent years watching GLP-1 medications become one of the most talked-about developments in modern medicine — and years declining to try them. She watched friends start. She watched colleagues go public. She remained unconvinced. "I'm just not a girl who just wants to do something because some of my friends are doing it," she told TODAY.com in an interview published August 10, 2026.

Then her father's health history caught up with her thinking.

Metz, born September 29, 1980, grew up watching her father struggle with obesity-related health complications. As she entered perimenopause, the combination of family history and the particular demands that hormone shift places on the body gave her a new framework for thinking about the medications she had long resisted. "I'm in perimenopause," she told PEOPLE, "and there were obesity issues within my family and with my father, and I felt like I've tried so many modalities, whether it was diets or therapy, and none of it really worked for me."

She has been dieting since the age of nine. She has tried group therapy. She has tried counting, restricting, and adjusting. "I just wanted to take care of myself," she said simply.

Once her doctors signed off, she said yes — and partnered with Ro, a telehealth company that provides GLP-1 medications. She resumed what she called her "GLP-1 journey" in March 2026, writing on Instagram that she was "being really intentional" about her usage. "For me, it wasn't just about weight," she wrote. "It was about feeling better, having more energy, and actually trusting the process instead of rushing it."

The most unexpected change, she said, was not physical.

Metz had lost approximately 100 pounds in the period before her GLP-1 use — a transformation she achieved through diet, strength training, and significant lifestyle changes. The medication, she made clear, was not the beginning of her health journey. It was a specific tool, chosen for specific reasons, at a specific moment in her life.

What surprised her most was what happened to her mind. "It's, like, unbelievable," she said of the reduction in what the medical community calls "food noise" — the constant, low-level preoccupation with eating and hunger that many people with obesity describe as a feature of daily life rather than a choice. "I admit I didn't believe it when people said they didn't deal with food noise," she told TODAY.com. She is now discovering, for the first time, the mental space that opens when that preoccupation quiets.

She is also clear-eyed about the judgment she expects. "I know people will judge me," she told PEOPLE. She preempted the most common criticism directly: "It's not the easy way out. I think a lot of people think, 'Oh, it's a magic wand,' and no, in fact, you have to be more diligent." She has incorporated strength training alongside the medication and is focused on longevity.

"I was nervous and scared," she told Fox News of the decision to start. "But it's good for me because I'm really putting myself first."

She has been dieting since she was nine years old. At 45, for the first time in decades, her mind is not preoccupied with food. That, by any measure, is worth saying out loud.

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